Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633078 | 0.96 | CYP19A1 (0.55) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11632637 | 0.91 | CYP3A4 (0.58) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11637149 | 0.89 | CYP19A1 (0.50) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11638108 | 0.86 | CYP3A4 (0.53) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11633847 | 0.85 | CYP3A4 (0.59) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11667558 | 0.83 | TP53 (0.46) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11632657 | 0.82 | TP53 (0.56) | CYP19A1TBXAS1ALDH1A1TP53 | |
| SCHEMBL11630883 | 0.82 | CYP3A4 (0.68) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11752321 | 0.82 | TP53 (0.54) | CYP19A1TBXAS1ALDH1A1TP53 | |
| SCHEMBL11753447 | 0.80 | TP53 (0.54) | CYP19A1TBXAS1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4078071-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-03-07 | — | — | US | disclosed |