⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20918303 | 0.63 | — | — | |
| SCHEMBL5027486 | 0.59 | — | — | |
| SCHEMBL150795 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL2120330 | 0.56 | — | — | |
| Bromide SCHEMBL406095 | 0.56 | — | — | |
| Magnesium SCHEMBL31500308 | 0.56 | — | — | |
| SCHEMBL5233 | 0.56 | — | — | |
| SCHEMBL18277651 | 0.56 | — | — | |
| Bromide SCHEMBL7135885 | 0.56 | — | — | |
| Hydrochloric Acid SCHEMBL4501345 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074893-A1 | SYNTHESIS OF QUINAZOLINE COMPOUNDS | GENENTECH, INC. (US) | 2025-03-06 | — | — | US | claimed |
| US-20250066297-A1 | COMPOUNDS USEFUL FOR THE PREPARATION OF VARIOUS AGROCHEMICALS AND MARKERS THEREOF | ADAMA AGAN LTD. (IL) | 2025-02-27 | — | — | US | claimed |
| US-20250059155-A1 | PROCESS FOR SYNTHESIS OF QUINAZOLINE COMPOUNDS | GENENTECH, INC. (US) | 2025-02-20 | — | — | US | claimed |
| US-12172982-B2 | Synthesis of quinazoline compounds | GENENTECH, INC. (US) | 2024-12-24 | — | — | US | claimed |
| EP-4476205-A1 | PROCESS FOR SYNTHESIS OF QUINAZOLINE COMPOUNDS | Genentech Inc. (US) | 2024-12-18 | — | — | EP | claimed |
| CN-119039340-A | Preparation method of diethylamino trialkoxysilane | 湖北华邦化学有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-116057052-B | Synthesis of quinazoline compounds | 基因泰克公司 | 2024-09-03 | — | — | CN | claimed |
| CN-118574820-A | Method for synthesizing quinazoline compounds | 基因泰克公司 | 2024-08-30 | — | — | CN | claimed |
| US-12071422-B2 | Process for synthesis of quinazoline compounds | GENENTECH, INC. (US) | 2024-08-27 | — | — | US | claimed |
| CN-118401112-A | Compounds for preparing various agrochemicals and markers thereof | 安道麦阿甘有限公司 | 2024-07-26 | — | — | CN | claimed |
| US-7205441-B2 | Method for producing tetrakis (fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-04-17 | — | — | US | claimed |
| EP-1318148-B1 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK CORP (KR) | 2005-01-12 | — | — | EP | claimed |
| US-6841688-B2 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK CORPORATION (KR) | 2005-01-11 | — | — | US | claimed |
| US-20030216598-A1 | Method for producing tetrakis ( fluoroaryl) borate-magnesium compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2003-11-20 | — | — | US | claimed |
| EP-1362860-A1 | Method for producing tetrakis (fluoroaryl) borate magnesium compound | Nippon Shokubai Co., Ltd. (JP) | 2003-11-19 | — | — | EP | claimed |
| US-20030114693-A1 | Method of preparing optically pure (R) - or (S) - tetrahydrofuranyl ketone | SK CORPORATION | 2003-06-19 | — | — | US | claimed |
| EP-1318148-A1 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK Corporation (KR) | 2003-06-11 | — | — | EP | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | claimed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | claimed |