Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TLR4 | O00206 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18928225 | 0.86 | PPARG (0.68) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11272884 | 0.85 | PPARG (0.67) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11636235 | 0.85 | SMN1; SMN2 (0.64) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL9853488 | 0.84 | MAPT (0.63) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL18928224 | 0.83 | PPARG (0.65) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL11276567 | 0.83 | PPARG (0.65) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL13603806 | 0.82 | MAPT (0.60) | PPARGSMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL10800720 | 0.82 | MAPT (0.64) | SMN1; SMN2MAPTLMNAALDH1A1TP53 | |
| SCHEMBL31384417 | 0.81 | MAPT (0.67) | SMN1; SMN2MAPTLMNAALDH1A1TP53 | |
| SCHEMBL333291 | 0.81 | MAPT (0.67) | SMN1; SMN2MAPTLMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |