⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629056 | 0.93 | KMT2A (0.52) | — | |
| SCHEMBL3992015 | 0.91 | KMT2A (0.56) | — | |
| SCHEMBL3993688 | 0.91 | KMT2A (0.56) | — | |
| 3-Oxotetradecanal SCHEMBL1301744 | 0.91 | KMT2A (0.56) | — | |
| SCHEMBL3990464 | 0.91 | KMT2A (0.56) | — | |
| SCHEMBL3987687 | 0.91 | KMT2A (0.56) | — | |
| SCHEMBL3877076 | 0.91 | KMT2A (0.56) | — | |
| 3-Oxodecanal SCHEMBL3646476 | 0.91 | KMT2A (0.56) | — | |
| SCHEMBL3986013 | 0.91 | KMT2A (0.56) | — | |
| SCHEMBL3992626 | 0.91 | KMT2A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066424-A | Kv3 modulators | 奥蒂福尼疗法有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-112646539-B | Near-infrared curing polyurethane acrylate adhesive | 江南大学 | 2022-02-01 | — | — | CN | claimed |
| CN-113022091-A | Application method of adhesive based on near-infrared curing | 江南大学 | 2021-06-25 | — | — | CN | claimed |
| CN-112646539-A | Near-infrared curing polyurethane acrylate adhesive | 江南大学 | 2021-04-13 | — | — | CN | claimed |
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | claimed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | claimed |
| CN-119100970-A | Bivalent inhibitor based on heat shock protein 90 and preparation method and application thereof | 中国药科大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-118267386-A | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-108472288-B | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-117263922-A | Heterocyclic compounds as AT2R agonists | 武汉人福创新药物研发中心有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-218710134-U | Reflective film and vehicle number plate | 常州华日升反光材料有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115066424-A | Kv3 modulators | 奥蒂福尼疗法有限公司 | 2022-09-16 | — | — | CN | disclosed |
| US-7537906-B2 | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone | Nomura, Nobuhiko (JP) | 2009-05-26 | — | — | US | disclosed |
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| US-20040229944-A1 | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |
| EP-1442742-A1 | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone | Nomura, Nobuhiko (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-0528380-A1 | Alkyl-aryl 1,3-propanedion silicone derivative and an external preparation for skin with the derivative compounded therein | SHISEIDO COMPANY LIMITED (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-4375434-A | Process for 6'-amino-penicillanoyloxymethyl penicillanate 1,1-dioxide | PFIZER INC. (US) | 1983-03-01 | — | — | US | disclosed |