Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28544917 | 0.76 | MC4R (0.40) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL21664467 | 0.72 | MC4R (0.41) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL13242286 | 0.72 | MC4R (0.41) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL20906905 | 0.71 | MC4R (0.44) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL22753497 | 0.71 | MC4R (0.44) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL5720551 | 0.71 | MC4R (0.44) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL16316010 | 0.71 | MC4R (0.44) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL81580 | 0.71 | MC4R (0.44) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL1699772 | 0.71 | MC4R (0.44) | MC4RCHRM2CHRM1ADRA2ADRD1 | |
| SCHEMBL23747986 | 0.69 | MC4R (0.35) | MC4RCHRM2CHRM1ADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083978-A | ANTIEPILEPTIC, TETRABENAZINE-ANTAGONISTIC, NICOTINE-LETHALITY INHIBITING | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1978-04-11 | — | — | US | disclosed |