Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 12/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247762 | 0.92 | SLC6A4 (0.85) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4457606 | 0.90 | SLC6A4 (0.81) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4035754 | 0.89 | SLC6A2 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4463258 | 0.89 | SLC6A4 (0.79) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL5244478 | 0.88 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL5248299 | 0.88 | SLC6A4 (0.78) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL1120086 | 0.87 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL12633242 | 0.87 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL1120084 | 0.87 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL11799175 | 0.87 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113869-A | MOOD MODIFIERS, ANOREXIA AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |