Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642396 | 0.98 | CYP2D6 (0.63) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL11644350 | 0.87 | CHRM3 (0.66) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| SCHEMBL2066395 | 0.82 | CHRM2 (0.47) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| SCHEMBL11610162 | 0.81 | CHRM2 (0.74) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| SCHEMBL6699352 | 0.81 | CHRM2 (0.74) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| SCHEMBL11737237 | 0.81 | CYP2D6 (0.55) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| SCHEMBL11733488 | 0.80 | CHRM2 (0.58) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL11608735 | 0.80 | CYP2D6 (0.72) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| Pridinol SCHEMBL143298 | 0.75 | CHRM2 (1.00) | CHRM2CHRM1CYP2D6KCNH2HTR1A | |
| Pridinol SCHEMBL363996 | 0.74 | CHRM2 (0.97) | CHRM2CHRM1CYP2D6KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118494-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |