Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.53 |
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | IGF1R | P08069 | 11/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944044 | 0.86 | CCNA2 (0.55) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL2069987 | 0.85 | CCNA2 (0.58) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12784240 | 0.85 | IGF1R (0.52) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL9944045 | 0.84 | CCNA2 (0.55) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12878137 | 0.84 | CCNA2 (0.56) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL16004492 | 0.84 | CCNA2 (0.53) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12784239 | 0.84 | CCNA2 (0.60) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL27871320 | 0.83 | CCNA2 (0.57) | CCNA2CDK2IGF1RNTRK1 | |
| Hydrochloric Acid SCHEMBL1164521 | 0.83 | CCNA2 (0.59) | CCNA2CDK2IGF1R | |
| Hydrochloric Acid SCHEMBL1164431 | 0.83 | CCNA2 (0.59) | CCNA2CDK2IGF1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053916-A1 | PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011019405-A1 | PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053916-A1 | PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS | TYMS, TYMP, DPYD | CCNA2 1047/4885CDK2 122/4885IGF1R 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.