Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.68 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648254 | 0.94 | AKR1C3 (0.76) | AKR1C3AKR1C2KDM4EAPAF1RECQL | |
| SCHEMBL20745310 | 0.86 | KDM4E (0.71) | AKR1C3AKR1C2KDM4EMAPTGFER | |
| SCHEMBL30638203 | 0.83 | KDM4E (0.75) | AKR1C3AKR1C2KDM4EAPAF1RECQL | |
| SCHEMBL4246571 | 0.83 | KDM4E (0.75) | AKR1C3AKR1C2KDM4EAPAF1RECQL | |
| SCHEMBL19260548 | 0.82 | AKR1C3 (0.61) | AKR1C3AKR1C2KDM4EAPAF1RECQL | |
| SCHEMBL351705 | 0.82 | MAPT (0.79) | AKR1C3AKR1C2KDM4EMAPTGFER | |
| SCHEMBL29744518 | 0.82 | MAPT (0.72) | AKR1C3AKR1C2KDM4ERECQLMAPT | |
| SCHEMBL2095055 | 0.82 | MAPT (0.72) | AKR1C3AKR1C2KDM4ERECQLMAPT | |
| SCHEMBL14598923 | 0.82 | AKR1C3 (0.78) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL4257100 | 0.81 | MAPT (0.68) | AKR1C3AKR1C2KDM4EMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124768-A | Process for preparing pure substituted 2,5-diarylamino-terephthalates and the corresponding free acids | HOECHST AKTIENGESELLSCHAFT | 1978-11-07 | — | — | US | disclosed |