Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645863 | 0.99 | CHRM2 (0.42) | CHRM2ADRA2AHRH3MEN1PARP1 | |
| SCHEMBL11646372 | 0.92 | CHRM2 (0.44) | CHRM2ADRA2AHRH3MEN1PARP1 | |
| SCHEMBL11645771 | 0.90 | CHRM2 (0.43) | CHRM2ADRA2AHRH3MEN1PARP1 | |
| SCHEMBL11735576 | 0.86 | CHRM2 (0.39) | CHRM2ADRA2AHRH3ALDH1A1TP53 | |
| SCHEMBL11735600 | 0.84 | CHRM2 (0.37) | CHRM2ADRA2AHRH3ATML3MBTL1 | |
| SCHEMBL11648505 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL11642560 | 0.81 | CHRM2 (0.49) | CHRM2ADRA2AHRH3MEN1PARP1 | |
| SCHEMBL11641338 | 0.81 | HRH3 (0.41) | HRH3 | |
| SCHEMBL11644765 | 0.80 | CHRM2 (0.47) | CHRM2ADRA2AHRH3MEN1PARP1 | |
| SCHEMBL11646599 | 0.80 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118494-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |