Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642778 | 0.85 | F10 (0.45) | LMNATSHRMAPK10HTTNPC1 | |
| SCHEMBL2740726 | 0.84 | TSHR (0.42) | LMNATSHRMAPK10HTTCA1 | |
| SCHEMBL11647613 | 0.81 | MAPK10 (0.47) | LMNATSHRMAPK10HTTALDH1A1 | |
| SCHEMBL11557022 | 0.76 | MAPK10 (0.47) | LMNATSHRMAPK10HTTALDH1A1 | |
| SCHEMBL16503311 | 0.74 | TSHR (0.50) | LMNATSHRMAPK10HTTCA1 | |
| SCHEMBL13730168 | 0.74 | CA1 (0.45) | LMNATSHRMAPK10HTTCA1 | |
| SCHEMBL12318023 | 0.72 | CYP2C9 (0.43) | LMNATSHRALDH1A1NPC1USP2 | |
| SCHEMBL892413 | 0.72 | MIF (0.76) | LMNATSHRHTTCA1CA2 | |
| SCHEMBL11394124 | 0.72 | F10 (0.45) | HTTALDH1A1L3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL11474972 | 0.71 | S1PR1 (0.52) | LMNATSHRMAPK10HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129568-A | 2-[3-Aryl-2-isoxazolin-5-yl]benzoates | MONSANTO COMPANY (US) | 1978-12-12 | — | — | US | disclosed |