Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645948 | 0.83 | HSD17B10 (0.72) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL11649419 | 0.79 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL11648139 | 0.76 | HSD17B10 (0.67) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL11649079 | 0.74 | HSD17B10 (0.65) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL11642854 | 0.74 | HSD17B10 (0.65) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL8145766 | 0.71 | CYP1A2 (0.67) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL11649909 | 0.69 | HSD17B10 (0.57) | HSD17B10CYP1A2CYP3A4BRD4SMN1; SMN2 | |
| SCHEMBL29025896 | 0.67 | CYP1A2 (0.61) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL8352639 | 0.67 | CYP1A2 (1.00) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 | |
| SCHEMBL10058644 | 0.67 | HSD17B10 (0.71) | HSD17B10CYP1A2CYP3A4BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | disclosed |