Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647216 | 1.00 | MAPT (0.58) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL10978025 | 0.85 | MAPT (0.61) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL10978028 | 0.85 | MAPT (0.61) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL11650965 | 0.83 | MAPT (0.58) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL11650968 | 0.83 | MAPT (0.58) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL11797950 | 0.77 | MAPT (0.61) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL11797944 | 0.77 | MAPT (0.61) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL11329238 | 0.76 | MAPT (1.00) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL205992 | 0.76 | MAPT (1.00) | MAPTTDP1L3MBTL1RAB9AMEN1 | |
| SCHEMBL16556 | 0.76 | MAPT (1.00) | MAPTTDP1L3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093613-A | Trisazo pigments containing two barbituric acid coupling components | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4043999-A | Methyl or methoxy substituted iminoisoindolinone pigments | CIBA-GEIGY CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |