Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 4/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SHBG | P04278 | 2/20 | 0.38 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517273 | 1.00 | CYP19A1 (0.67) | CYP19A1CYP17A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL10332361 | 1.00 | CYP19A1 (0.67) | CYP19A1CYP17A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL12394873 | 0.82 | MEN1 (0.57) | CYP19A1CYP17A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL1114465 | 0.82 | MEN1 (0.57) | CYP19A1CYP17A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL17704809 | 0.82 | MEN1 (0.57) | CYP19A1CYP17A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL17704817 | 0.80 | CYP19A1 (0.58) | CYP19A1CYP17A1AKR1B10AKR1B1OR51E2 | |
| SCHEMBL9965232 | 0.80 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2G6PD | |
| SCHEMBL334387 | 0.80 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2G6PD | |
| SCHEMBL334388 | 0.80 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2G6PD | |
| SCHEMBL4584277 | 0.80 | CYP19A1 (1.00) | CYP19A1AKR1B10AKR1B1OR51E2G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110326-A | STEROIDS, CURARE-TYPE | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1978-08-29 | — | — | US | claimed |
| US-4110326-A | STEROIDS, CURARE-TYPE | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1978-08-29 | — | — | US | disclosed |