Naphthoic Acid

Naphthoic Acid

SCHEMBL1165073

O=C([O-])c1cccc2ccccc12.O=C([O-])c1cccc2ccccc12.[O-2].[Zr+4]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.61
NR4A2 P43354 1/20 0.61
NR4A3 Q92570 1/20 0.61
MMP3 P08254 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
PTPN1 P18031 1/20 0.53
CDC25B P30305 1/20 0.53
PLK1 P53350 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.47
PTK2B Q14289 1/20 0.47
ALDH1A1 P00352 5/20 0.47
HPGD P15428 5/20 0.47
KDM4E B2RXH2 3/20 0.47
POLB P06746 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 4/20 0.46
MEN1 O00255 3/20 0.46
LMNA P02545 3/20 0.46
NPSR1 Q6W5P4 3/20 0.46
TDP1 Q9NUW8 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthoic Acid SCHEMBL29774135 0.98 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL914186 0.98 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL914808 0.96 NR4A1 (0.61) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL10566925 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL6916273 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL11105015 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL6912751 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL6912561 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL10496191 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8
Naphthoic Acid SCHEMBL10550054 0.94 NR4A1 (0.63) NR4A1NR4A2NR4A3MMP3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952525-B1 STUDLESS WINTER TIRE SUMITOMO RUBBER IND (JP) 2017-05-10 EP disclosed
EP-2952525-A1 STUDLESS WINTER TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-12-09 EP disclosed
US-20150329716-A1 STUDLESS WINTER TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-11-19 US disclosed
US-8962752-B2 Rubber composition and tire using the same as well as modified conjugated diene-based polymer and method for producing the same BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
EP-2253664-B1 RUBBER COMPOSITION AND TIRES USING THE SAME, AS WELL AS MODIFIED CONJUGATE DIENE POLYMER AND MANUFACTURING METHOD THEREOF BRIDGESTONE CORP (JP) 2014-11-05 EP disclosed
US-20140228525-A1 RUBBER COMPOSITION AND TIRE USING THE SAME AS WELL AS MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING THE SAME BRIDGESTONE CORPORATION (JP) 2014-08-14 US disclosed
US-8729184-B2 Rubber composition and tire using the same as well as modified conjugated diene-based polymer and method for producing the same BRIDGESTONE CORPORATION (JP) 2014-05-20 US disclosed
EP-1860136-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION THEREOF JSR CORP (JP) 2013-01-09 EP disclosed
EP-1790666-B1 PROCESS FOR PRODUCING CONJUGATED DIOLEFIN (CO)POLYMER RUBBER, CONJUGATED DIOLEFIN (CO)POLYMER RUBBER, RUBBER COMPOSITION, AND TIRE JSR CORP (JP) 2011-09-07 EP disclosed
US-20110184114-A1 RUBBER COMPOSITION AND TIRE USING THE SAME AS WELL AS MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING THE SAME BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
US-20110046263-A1 TIRE PREPARED BY USING RUBBER COMPOSITION CONTAINING MODIFIED POLYMER BRIDGESTONE CORPORATION (JP) 2011-02-24 US disclosed
US-7893164-B2 Process for producing conjugated diolefin (Co) polymer rubber, conjugated diolefin (Co) polymer rubber, rubber composition, and tire JSR CORPORATION (JP) 2011-02-22 US disclosed
EP-2253664-A1 RUBBER COMPOSITION AND TIRES USING THE SAME, AS WELL AS MODIFIED CONJUGATE DIENE POLYMER AND MANUFACTURING METHOD THEREOF Bridgestone Corporation (JP) 2010-11-24 EP disclosed
US-7700686-B2 Process for producing modified polymer, modified polymer obtained by the process, and rubber composition thereof JSR CORPORATION (JP) 2010-04-20 US disclosed
US-20080188613-A1 Process For Producing Modified Polymer, Modified Polymer Obtained By The Process, And Rubber Composition Thereof JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20080045664-A1 Process for Producing Conjugated Diolefin (Co) Polymer Rubber, Conjugated Diolefin (Co) Polymer Rubber, Rubber Composition, and Tire JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1860136-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION THEREOF JSR Corporation (JP) 2007-11-28 EP disclosed
EP-1790666-A1 PROCESS FOR PRODUCING CONJUGATED DIOLEFIN (CO)POLYMER RUBBER, CONJUGATED DIOLEFIN (CO)POLYMER RUBBER, RUBBER COMPOSITION, AND TIRE JSR Corporation (JP) 2007-05-30 EP disclosed