Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 6/20 | 0.56 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165351 | 1.00 | TEK (0.56) | TEKKDRHDAC1HDAC6HDAC2 | |
| SCHEMBL2128518 | 0.91 | HDAC4 (0.58) | TEKKDRHDAC1HDAC6HDAC2 | |
| SCHEMBL2128515 | 0.91 | HDAC4 (0.58) | TEKKDRHDAC1HDAC6HDAC2 | |
| Hydrochloric Acid SCHEMBL1165269 | 0.87 | TEK (0.50) | TEKKDRHDAC1HDAC6HDAC2 | |
| SCHEMBL1165170 | 0.87 | HDAC1 (0.61) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL1165168 | 0.87 | HDAC1 (0.61) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL2128745 | 0.84 | HDAC2 (0.64) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL2128746 | 0.84 | HDAC2 (0.64) | HDAC1HDAC6HDAC2HDAC3HDAC8 | |
| SCHEMBL3439437 | 0.83 | MEN1 (0.62) | TEKKDRHDAC1HDAC6HDAC2 | |
| SCHEMBL3439452 | 0.80 | HDAC1 (0.63) | HDAC1HDAC6HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451790-A1 | HISTONE DEACETYLASE INHIBITORS | Anthem Biosciences Private Limited (IN) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011021209-A1 | HISTONE DEACETYLASE INHIBITORS | PORTSMOUTH TECHNOLOGIES LLC (US) | 2011-02-24 | — | — | WO | disclosed |