Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449243 | 0.93 | NPC1 (0.46) | NPC1JAK2RAB9APAX8EGFR | |
| SCHEMBL8626950 | 0.91 | NPC1 (0.49) | NPC1JAK2RAB9APAX8MAPT | |
| SCHEMBL1438703 | 0.89 | EGFR (0.55) | NPC1JAK2RAB9APAX8EGFR | |
| SCHEMBL5715744 | 0.89 | NPC1 (0.51) | NPC1JAK2RAB9APAX8MAPT | |
| SCHEMBL2419505 | 0.89 | NPC1 (0.51) | NPC1JAK2RAB9APAX8MAPT | |
| SCHEMBL25225974 | 0.89 | NPC1 (0.51) | NPC1JAK2RAB9APAX8MAPT | |
| SCHEMBL9876834 | 0.89 | NPC1 (0.51) | NPC1JAK2RAB9APAX8MAPT | |
| SCHEMBL10490562 | 0.89 | NPC1 (0.51) | NPC1JAK2RAB9APAX8MAPT | |
| SCHEMBL9185996 | 0.89 | NPC1 (0.51) | NPC1JAK2RAB9APAX8MAPT | |
| Hydrochloric Acid SCHEMBL11650785 | 0.87 | NPC1 (0.50) | NPC1JAK2RAB9APAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119622-A | Pyrazolonylazoaniline or aminonaphtyl compounds for copying processes | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-10 | — | — | US | disclosed |