⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19641 | 0.78 | TSHR (0.62) | — | |
| SCHEMBL8767066 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL509714 | 0.75 | — | — | |
| SCHEMBL8767061 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL42883 | 0.73 | — | — | |
| SCHEMBL9343994 | 0.73 | — | — | |
| SCHEMBL16922278 | 0.73 | — | — | |
| SCHEMBL10493669 | 0.73 | — | — | |
| SCHEMBL21220135 | 0.72 | TSHR (0.40) | — | |
| SCHEMBL4370358 | 0.72 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264038-B1 | Optically active dibenzazepine derivatives | NIPPON SODA CO (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-8507669-B2 | Optically active dibenzazepine derivatives | NIPPON SODA CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2264038-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | Nippon Soda Co., Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |