Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129794 | 0.90 | TAAR1 (0.47) | S1PR1S1PR3S1PR2S1PR4TAAR1 | |
| SCHEMBL5323248 | 0.89 | S1PR1 (0.49) | S1PR1S1PR3S1PR2S1PR4SIGMAR1 | |
| SCHEMBL172466 | 0.89 | S1PR1 (0.49) | S1PR1S1PR3S1PR2S1PR4SIGMAR1 | |
| SCHEMBL14528095 | 0.80 | S1PR1 (0.45) | S1PR1S1PR3S1PR2S1PR4TAAR1 | |
| SCHEMBL27378825 | 0.80 | S1PR1 (0.49) | S1PR1S1PR3S1PR2S1PR4SIGMAR1 | |
| SCHEMBL12032154 | 0.79 | S1PR1 (0.48) | S1PR1S1PR3S1PR2S1PR4SIGMAR1 | |
| SCHEMBL29032102 | 0.78 | S1PR1 (0.55) | S1PR1S1PR3S1PR2S1PR4SIGMAR1 | |
| SCHEMBL6654413 | 0.78 | HRH3 (0.48) | S1PR1S1PR3S1PR2S1PR4TAAR1 | |
| SCHEMBL11134033 | 0.77 | S1PR2 (0.51) | S1PR1S1PR3S1PR2S1PR4SIGMAR1 | |
| SCHEMBL29268867 | 0.77 | TAAR1 (0.55) | SIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097462-A | OXIDATIVE COUPLING OF A PHENOL, PRECIPITATION, MANGANESE (II) HYDROXYOXIME CHELATE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-3972851-A | Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3965069-A | Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3956242-A | Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |