Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.32 |
| ▸ | QPCT | Q16769 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366603 | 0.84 | HRH4 (0.34) | HRH4HRH2QPCT | |
| SCHEMBL11369824 | 0.81 | HRH4 (0.37) | HRH4HRH2QPCTNAMPT | |
| SCHEMBL11369819 | 0.81 | HRH4 (0.37) | HRH4HRH2QPCTNAMPT | |
| SCHEMBL11368760 | 0.80 | — | — | |
| SCHEMBL11360059 | 0.77 | KDM4C (0.32) | HRH2 | |
| SCHEMBL11369843 | 0.77 | HRH4 (0.34) | HRH4HRH2QPCTNAMPT | |
| SCHEMBL11361858 | 0.77 | QPCT (0.31) | QPCT | |
| SCHEMBL11360061 | 0.77 | KDM4C (0.32) | HRH2 | |
| SCHEMBL11359454 | 0.77 | BCHE (0.32) | HTR1AQPCT | |
| SCHEMBL11367522 | 0.77 | HRH4 (0.37) | HRH4HRH2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |