SCHEMBL11664352

SCHEMBL11664352

Cc1ccc(C(=O)O)cc1C(=O)O.[Si]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 2/20 0.50
MYC P01106 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
TPMT P51580 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ESR1 P03372 1/20 0.47
ALOX15 P16050 1/20 0.47
PTPN7 P35236 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TP53 P04637 1/20 0.46
GRM1 Q13255 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69633 0.98 TSHR (0.53) TSHRALDH1A1MYCKDM4ECA12
SCHEMBL28858438 0.96 TSHR (0.52) TSHRALDH1A1MYCKDM4ECA12
Benzene SCHEMBL27546363 0.96 KDM4E (0.55) TSHRALDH1A1MYCKDM4ESMN1; SMN2
Ethane SCHEMBL27317410 0.96 TSHR (0.52) TSHRALDH1A1MYCKDM4ECA12
Bicarbonate SCHEMBL27496907 0.96 TSHR (0.52) TSHRALDH1A1MYCKDM4ECA12
Hydrochloric Acid SCHEMBL10448118 0.96 TSHR (0.52) TSHRALDH1A1MYCKDM4ECA12
Hydrochloric Acid SCHEMBL16610510 0.96 TSHR (0.52) TSHRALDH1A1MYCKDM4ECA12
Ammonia Solution, Strong SCHEMBL27537561 0.96 TSHR (0.52) TSHRALDH1A1MYCKDM4ECA12
Acetic Acid SCHEMBL27497245 0.94 TSHR (0.50) TSHRALDH1A1MYCKDM4ESMN1; SMN2
Ethylene SCHEMBL27479147 0.94 TSHR (0.50) TSHRALDH1A1MYCKDM4ECA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4127654-A Compositions and methods containing beta substituted allyl alcohols, sulfuric acid esters thereof, phosphoric acid esters thereof, alkanoyl esters thereof and alkylene oxide ethers thereof KAO SOAP CO., LTD. (JP) 1978-11-28 US disclosed