Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665505 | 0.86 | PTGER4 (0.39) | PTGER4PTGER3PTGER2CYP1A2FKBP1A | |
| SCHEMBL4994022 | 0.82 | PTGER4 (0.47) | PTGER4PTGER3PTGER2ALDH1A1USP2 | |
| SCHEMBL4994025 | 0.82 | PTGER4 (0.47) | PTGER4PTGER3PTGER2ALDH1A1USP2 | |
| SCHEMBL4909119 | 0.79 | ABL1 (0.38) | PTGER4PTGER3PTGER2ALDH1A1USP2 | |
| SCHEMBL11664469 | 0.77 | PTGER4 (0.61) | PTGER4PTGER3PTGER2 | |
| SCHEMBL11663532 | 0.74 | PTGER4 (0.50) | PTGER4PTGER3PTGER2 | |
| SCHEMBL265785 | 0.70 | TDP1 (0.39) | PTGER4PTGER3PTGER2ALDH1A1USP2 | |
| SCHEMBL11624113 | 0.69 | PTGER4 (0.46) | PTGER4PTGER3PTGER2 | |
| SCHEMBL16088758 | 0.69 | PTGER4 (0.46) | PTGER4PTGER3PTGER2 | |
| SCHEMBL27932302 | 0.68 | CYP1A2 (0.52) | ALDH1A1USP2ALOX15TDP1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115401-A | RESPIRATORY DISORDERS | LABAZ (FR) | 1978-09-19 | — | — | US | disclosed |