Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | NEK4 | P51957 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.39 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24325919 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL3234142 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL11665011 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6389932 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| Hydrochloric Acid SCHEMBL2322263 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL20843407 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2HTR2AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL18553838 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL9593230 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL10582023 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6724867 | 0.76 | MTOR (0.58) | SMN1; SMN2ALDH1A1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088771-A | 1-Lower alkyl-4,5-dihydro-5-phenyl-2-lower alkoxy carbonylaminoimidazoles and substituted phenyl derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1978-05-09 | — | — | US | disclosed |