Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.49 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.49 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.49 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759503 | 0.89 | POLB (0.53) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL1759557 | 0.85 | CYP2D6 (0.53) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL10398674 | 0.85 | POLB (0.53) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL1095777 | 0.85 | POLB (0.53) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL1096734 | 0.85 | POLB (0.53) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL10811806 | 0.78 | SUMO2 (0.50) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL9770459 | 0.78 | SUMO2 (0.50) | POLBCYP2D6SENP2SENP1SUMO2 | |
| Azobenzene SCHEMBL28447456 | 0.77 | POLB (0.71) | POLBCYP2D6SENP2SENP1SUMO2 | |
| Azobenzene SCHEMBL27983410 | 0.77 | POLB (0.71) | POLBCYP2D6SENP2SENP1SUMO2 | |
| SCHEMBL23787571 | 0.76 | APP (0.59) | POLBCYP2D6SENP2SENP1SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128544-A | DYES FOR NATURAL OR REGENERATED CELLULOSE | SANDOZ LTD. (CH) | 1978-12-05 | — | — | US | disclosed |