Naphthalene

Naphthalene

SCHEMBL11670474

CCNCC(=O)c1ccccc1.c1ccc2ccccc2c1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
MAPT P10636 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
MEN1 O00255 4/20 0.52
HPGD P15428 4/20 0.52
KDM4E B2RXH2 3/20 0.52
CYP3A4 P08684 3/20 0.52
MAPK1 P28482 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 1/20 0.52
CES1 P23141 1/20 0.52
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
ALDH1A1 P00352 8/20 0.47
LMNA P02545 2/20 0.47
PTPN1 P18031 2/20 0.46
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
AGTR1 P30556 3/20 0.45
CYP1A2 P05177 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046322 0.94 KMT2A (0.58) KMT2AMAPTSMN1; SMN2MEN1HPGD
Hydrochloric Acid SCHEMBL11607572 0.92 KMT2A (0.56) KMT2AMAPTSMN1; SMN2MEN1HPGD
SCHEMBL5932634 0.82 HPGD (0.68) KMT2AMAPTSMN1; SMN2MEN1HPGD
Bromide SCHEMBL10777716 0.80 HPGD (0.65) KMT2AMAPTSMN1; SMN2MEN1HPGD
Hydrochloric Acid SCHEMBL9432569 0.80 HPGD (0.65) KMT2AMAPTSMN1; SMN2MEN1HPGD
SCHEMBL11137757 0.79 HPGD (0.54) KMT2AMAPTSMN1; SMN2MEN1HPGD
Propiophenone SCHEMBL27783343 0.79 MAPT (0.62) KMT2AMAPTSMN1; SMN2MEN1HPGD
SCHEMBL18306239 0.78 HPGD (0.62) KMT2AMAPTSMN1; SMN2MEN1HPGD
SCHEMBL18503706 0.78 HPGD (0.62) KMT2AMAPTSMN1; SMN2MEN1HPGD
Hydrochloric Acid SCHEMBL11756049 0.77 KDM4E (0.50) KMT2AMAPTMEN1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039526-A PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed
US-4039539-A 1,2,4-Triazole-azo-aniline cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed