Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873468 | 0.84 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL11141219 | 0.81 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL21177760 | 0.80 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL8851612 | 0.79 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL27666403 | 0.78 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL28848601 | 0.78 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL73498 | 0.78 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL11141004 | 0.77 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL2554590 | 0.76 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 | |
| SCHEMBL3658885 | 0.75 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4040977-A | HALOACETAMIDE OR THIOCYANOACETAMIDE-ALCOHOL-FORMALDEHYDE CONDENSATES | STERLING DRUG INC. (US) | 1977-08-09 | — | — | US | disclosed |