Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4362688 | 0.94 | — | — | |
| Bicarbonate SCHEMBL21056247 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9119324 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL1289595 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL21056248 | 0.94 | — | — | |
| Bicarbonate SCHEMBL262024 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1508589 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9079932 | 0.88 | — | — | |
| Bicarbonate SCHEMBL6013375 | 0.88 | — | — | |
| Bicarbonate SCHEMBL10909607 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034756-A | Osmotically driven fluid dispenser | ALZA CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-3995631-A | Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient | ALZA CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |