Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672622 | 1.00 | TDP1 (0.69) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11672812 | 0.99 | TDP1 (0.70) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11671817 | 0.92 | TDP1 (0.74) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11110717 | 0.89 | TDP1 (0.67) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9852597 | 0.88 | TDP1 (0.78) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9342519 | 0.88 | TDP1 (0.71) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10785951 | 0.87 | TDP1 (0.53) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11116172 | 0.87 | TDP1 (0.68) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11673152 | 0.85 | TDP1 (0.70) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11671733 | 0.85 | TDP1 (0.64) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001005-A | PREEMERGENE, POSTEMERGENCE | MOBIL OIL CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |