Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.82 |
| ▸ | BCHE | P06276 | 16/20 | 0.76 |
| ▸ | ACHE | P22303 | 8/20 | 0.76 |
| ▸ | CNR2 | P34972 | 6/20 | 0.76 |
| ▸ | CNR1 | P21554 | 7/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672542 | 0.97 | APP (0.87) | APPBCHEACHECNR2CNR1 | |
| Oxalic Acid SCHEMBL11672214 | 0.95 | APP (0.84) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11674118 | 0.94 | APP (0.78) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11672546 | 0.91 | APP (0.87) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11672709 | 0.90 | APP (1.00) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11730748 | 0.90 | APP (0.85) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL2403633 | 0.90 | APP (1.00) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11673509 | 0.90 | APP (0.85) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11726658 | 0.90 | APP (0.82) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11672403 | 0.90 | APP (0.75) | APPBCHEACHECNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |