Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672611 | 1.00 | PLCG1 (0.79) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11101773 | 0.91 | PLCG1 (0.66) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11305923 | 0.91 | PLCG1 (0.66) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11796154 | 0.90 | PLCG1 (0.75) | PLCG1ALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL11673833 | 0.90 | PLCG1 (0.65) | PLCG1ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL11673831 | 0.90 | PLCG1 (0.65) | PLCG1ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL11773847 | 0.89 | PLCG1 (0.89) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11868041 | 0.89 | PLCG1 (0.64) | PLCG1ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL10412275 | 0.89 | PLCG1 (1.00) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11097617 | 0.89 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |