Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.68 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.68 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.68 |
| ▸ | RARB | P10826 | 1/20 | 0.68 |
| ▸ | RARG | P13631 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | PTGFR | P43088 | 2/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960741 | 0.90 | PTGIR (0.78) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL23352919 | 0.90 | PTGIR (0.78) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL5965091 | 0.90 | PTGIR (0.78) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL960482 | 0.89 | PTGIR (0.83) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL11672375 | 0.84 | PTGIR (0.57) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL2630491 | 0.83 | PTGIR (0.80) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL23352784 | 0.83 | PTGIR (0.80) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL29926857 | 0.83 | PTGIR (0.80) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL23352618 | 0.83 | PTGIR (0.80) | PTGIRPTGER2PTGER4TSHRHPGD | |
| SCHEMBL29565577 | 0.83 | PTGIR (0.80) | PTGIRPTGER2PTGER4TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056562-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1977-11-01 | — | — | US | claimed |
| US-4056562-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1977-11-01 | — | — | US | disclosed |
| US-4041050-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxo-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3997588-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1976-12-14 | — | — | US | disclosed |