Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.62 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065430 | 1.00 | TDP1 (0.62) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL11674589 | 1.00 | TDP1 (0.62) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL7040792 | 0.94 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL7028779 | 0.94 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL7030196 | 0.94 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL11063940 | 0.94 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL9436142 | 0.94 | TDP1 (0.61) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL11691341 | 0.92 | TDP1 (0.65) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL11691346 | 0.92 | TDP1 (0.65) | TDP1MAPTHPGDNR1I2SLC22A6 | |
| SCHEMBL11688218 | 0.92 | TDP1 (0.60) | TDP1MAPTHPGDNR1I2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |