SCHEMBL11677347

SCHEMBL11677347

O=C(ON=C1CCCCC1Cl)c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 3/20 0.40
MEN1 O00255 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA5 P30532 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNA4 P43681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11676515 0.88 PTPN2 (0.38) L3MBTL1ALDH1A1KMT2AMEN1KDM4E
SCHEMBL11681156 0.88 KMT2A (0.47) RAB9ASMN1; SMN2NPC1L3MBTL1ALDH1A1
SCHEMBL11679732 0.87 KMT2A (0.45) L3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL11680068 0.86 KMT2A (0.46) RAB9ASMN1; SMN2NPC1L3MBTL1ALDH1A1
SCHEMBL11676952 0.86 KMT2A (0.46) RAB9ASMN1; SMN2NPC1L3MBTL1ALDH1A1
SCHEMBL11676830 0.86 KMT2A (0.44) L3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL11679560 0.86 KMT2A (0.44) L3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL11678219 0.85 MAPK1 (0.48) RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A
SCHEMBL11680054 0.84 MAPT (0.53) RAB9ASMN1; SMN2NPC1L3MBTL1TDP1
SCHEMBL11678450 0.84 MAPK1 (0.47) RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059625-A Certain oxime compositions and their use in controlling fungi STAUFFER CHEMICAL COMPANY (US) 1977-11-22 US disclosed
US-4007227-A Certain oxime compositions and their use in controlling fungi STAUFFER CHEMICAL COMPANY (US) 1977-02-08 US disclosed