Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11680599 | 0.87 | CNR2 (0.41) | CNR2CNR1HRH3KMT2A | |
| Hydrochloric Acid SCHEMBL11678033 | 0.81 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL11678770 | 0.81 | CNR2 (0.44) | CNR2CNR1THRATHRBHTR2A | |
| SCHEMBL11680487 | 0.77 | CNR2 (0.39) | CNR2CNR1THRATHRB | |
| SCHEMBL11678224 | 0.77 | CNR2 (0.46) | CNR2CNR1HTR2A | |
| Hydrochloric Acid SCHEMBL11677294 | 0.76 | CNR2 (0.39) | CNR2CNR1KMT2ATHRATHRB | |
| Hydrochloric Acid SCHEMBL11678139 | 0.76 | CNR1 (0.33) | CNR2CNR1 | |
| SCHEMBL11677068 | 0.76 | CNR1 (0.36) | CNR2CNR1 | |
| SCHEMBL11681854 | 0.76 | CNR1 (0.37) | CNR2CNR1 | |
| SCHEMBL11810292 | 0.75 | CNR2 (0.40) | CNR2CNR1ESR1HRH3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020163-A | Use of heterocyclic esters of 5H-[1]benzopyrano [3,4-b]pyridines as analgesics | SHARPS ASSOCIATES (US) | 1977-04-26 | — | — | US | disclosed |