Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679010 | 0.99 | — | — | |
| SCHEMBL11751953 | 0.92 | — | — | |
| SCHEMBL11678435 | 0.91 | — | — | |
| SCHEMBL11753863 | 0.87 | — | — | |
| SCHEMBL11749286 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL11745738 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL11679783 | 0.79 | — | — | |
| SCHEMBL11735384 | 0.75 | CNR1 (0.59) | — | |
| SCHEMBL11738579 | 0.75 | — | — | |
| SCHEMBL31545877 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029665-A | ANTICONVULSANTS | ABBOTT LABORATORIES (US) | 1977-06-14 | — | — | US | disclosed |
| US-4020163-A | Use of heterocyclic esters of 5H-[1]benzopyrano [3,4-b]pyridines as analgesics | SHARPS ASSOCIATES (US) | 1977-04-26 | — | — | US | disclosed |