Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.41 |
| ▸ | CNR1 | P21554 | 7/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
| ▸ | TRPV2 | Q9Y5S1 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11676889 | 0.93 | CNR2 (0.37) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11680076 | 0.86 | CNR2 (0.55) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11680357 | 0.82 | CNR2 (0.39) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11678408 | 0.79 | CNR2 (0.44) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11680616 | 0.77 | CNR2 (0.47) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11678224 | 0.75 | CNR2 (0.46) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11678393 | 0.74 | CNR2 (0.46) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11681854 | 0.73 | CNR1 (0.37) | CNR2CNR1 | |
| SCHEMBL11741078 | 0.72 | CNR2 (0.76) | CNR2CNR1OPRM1TRPV1TRPA1 | |
| SCHEMBL11636642 | 0.72 | CNR2 (0.49) | CNR2CNR1OPRM1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020163-A | Use of heterocyclic esters of 5H-[1]benzopyrano [3,4-b]pyridines as analgesics | SHARPS ASSOCIATES (US) | 1977-04-26 | — | — | US | disclosed |