Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678866 | 0.84 | POLB (0.54) | HPGDTSHRSIRT1POLBSMN1; SMN2 | |
| SCHEMBL11682076 | 0.84 | HPGD (0.41) | DPP4HPGDTSHRSIRT1CACNA1G | |
| SCHEMBL7687455 | 0.79 | HPGD (0.50) | DPP4HPGDTSHRSIRT1GRM2 | |
| SCHEMBL7687450 | 0.79 | HPGD (0.50) | DPP4HPGDTSHRSIRT1GRM2 | |
| SCHEMBL11678485 | 0.77 | DRD4 (0.56) | — | |
| SCHEMBL29254189 | 0.75 | HPGD (0.49) | DPP4HPGDTSHRSIRT1POLB | |
| SCHEMBL29254194 | 0.75 | HPGD (0.49) | DPP4HPGDTSHRSIRT1POLB | |
| SCHEMBL7685677 | 0.71 | CYP19A1 (0.49) | HPGDTSHRPOLBALDH1A1 | |
| SCHEMBL7685673 | 0.71 | CYP19A1 (0.49) | HPGDTSHRPOLBALDH1A1 | |
| SCHEMBL9209885 | 0.71 | HPGD (0.42) | DPP4HPGDTSHRGRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |