Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677949 | 1.00 | CYP3A4 (0.52) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL225460 | 0.98 | CYP3A4 (0.53) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL5076284 | 0.92 | CYP3A4 (0.48) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL8437006 | 0.89 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL10497089 | 0.88 | CYP3A4 (0.48) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL11311699 | 0.87 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL29042204 | 0.86 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL8436733 | 0.84 | CYP3A4 (0.39) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL22729167 | 0.84 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL18650062 | 0.83 | CYP3A4 (0.44) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012399-A | ULTRAVIOLET LIGHT ABSORBERS AND STABILIZERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1977-03-15 | — | — | US | disclosed |
| US-3959220-A | Polymer additives comprising transition metal complexes with trivalent phosphorous compounds | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-05-25 | — | — | US | disclosed |