SCHEMBL11680353

SCHEMBL11680353

CCCC(Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
KCNN4 O15554 3/20 0.41
CYP1A2 P05177 3/20 0.38
TAAR1 Q96RJ0 1/20 0.38
KIF11 P52732 3/20 0.37
SIGMAR1 Q99720 2/20 0.36
LMNA P02545 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
MAPK1 P28482 1/20 0.36
NFKB1 P19838 1/20 0.36
SCN1A P35498 1/20 0.36
MTOR P42345 1/20 0.36
RAB9A P51151 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28164030 0.86 TSHR (0.42) TSHRKCNN4CYP1A2TAAR1KIF11
SCHEMBL27641579 0.85 TSHR (0.41) TSHRKCNN4KIF11SIGMAR1MEN1
Ammonia Solution, Strong SCHEMBL11757631 0.81 HSP90AA1 (0.40) TSHRSIGMAR1MAPK1SMN1; SMN2MEN1
SCHEMBL6680627 0.81 TSHR (0.46) TSHRKCNN4CYP1A2TAAR1KIF11
SCHEMBL23781410 0.80 TSHR (0.50) TSHRKCNN4CYP1A2TAAR1KIF11
SCHEMBL6686379 0.79 TSHR (0.44) TSHRKCNN4CYP1A2TAAR1SIGMAR1
SCHEMBL4284381 0.77 ESR1 (0.38) KCNN4LMNARAB9AESR1ESR2
SCHEMBL15302733 0.77 TSHR (0.42) TSHRKCNN4CYP1A2TAAR1KIF11
SCHEMBL27668389 0.77 KCNN4 (0.42) TSHRKCNN4CYP1A2TAAR1KIF11
SCHEMBL2276136 0.76 TSHR (0.46) TSHRKCNN4CYP1A2TAAR1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022080354-A1 THERMOPLASTIC POLYESTER ELASTOMER RESIN COMPOSITION AND METHOD FOR PRODUCING SAME 東洋紡株式会社 2022-04-21 WO disclosed
US-20190091166-A1 BIOABSORBABLE SHEET OR FILM YOSHIDA YASUHIRO (JP) 2019-03-28 US disclosed
EP-3427762-A1 BIOABSORBABLE SHEET OR FILM Yoshida, Yasuhiro (JP) 2019-01-16 EP disclosed
EP-2543755-B1 CELLULOSE NANOFIBERS, METHOD FOR PRODUCING SAME, COMPOSITE RESIN COMPOSITION AND MOLDED BODY OLYMPUS CORP (JP) 2018-02-14 EP disclosed
EP-2905291-B1 METHOD FOR PRODUCING CELLULOSE NANOFIBERS OLYMPUS CORP (JP) 2017-04-12 EP disclosed
EP-2905291-A1 CELLULOSE NANOFIBER AND METHOD FOR PRODUCING SAME, COMPOSITE RESIN COMPOSITION, AND MOLDED ARTICLE Olympus Corporation (JP) 2015-08-12 EP disclosed
US-20150031804-A1 CELLULOSE NANOFIBERS AND METHOD FOR PRODUCING THE SAME, COMPOSITE RESIN COMPOSITION, AND MOLDED BODY OLYMPUS CORPORATION (JP) 2015-01-29 US disclosed
EP-2543755-A1 CELLULOSE NANOFIBERS, METHOD FOR PRODUCING SAME, COMPOSITE RESIN COMPOSITION AND MOLDED BODY Olympus Corporation (JP) 2013-01-09 EP disclosed
US-20120328877-A1 CELLULOSE NANOFIBERS, METHOD FOR PRODUCING SAME, COMPOSITE RESIN COMPOSITION AND MOLDED BODY OLYMPUS CORPORATION (JP) 2012-12-27 US disclosed
US-4034011-A 1,1-Diphenyl-4-(substituted-amino)butanes ELI LILLY AND COMPANY (US) 1977-07-05 US disclosed