Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL11440735 | 1.00 | FFAR3 (0.37) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL26343 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL60307 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL59116 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL1901678 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL18109766 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL609551 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL215989 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL2231460 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 | |
| Methacrylic Acid SCHEMBL194260 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054722-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-18 | — | — | US | disclosed |