Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777892 | 0.86 | HTT (0.45) | HSD17B10HTTNPSR1KDM4EHPGD | |
| SCHEMBL11773757 | 0.84 | HSD17B10 (0.58) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL11775218 | 0.83 | HTT (0.43) | HSD17B10HTTNPSR1KDM4EHPGD | |
| SCHEMBL11772595 | 0.83 | HSD17B10 (0.43) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL11780315 | 0.83 | HSD17B10 (0.57) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL11686443 | 0.77 | HTT (0.50) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL15330081 | 0.77 | HSD17B10 (0.47) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL11219412 | 0.75 | HTT (1.00) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL29368627 | 0.75 | HTT (1.00) | HSD17B10HTTNPSR1KDM4EMAPT | |
| SCHEMBL5987289 | 0.74 | AR (0.62) | HSD17B10HTTNPSR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941882-A | Rodenticidal imidazo-pyridines | ELI LILLY AND COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-4031107-A | Method for introducing amino groups into benzimidazole or imidazopyridine compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |