Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29884583 | 1.00 | STING1 (1.00) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL22216234 | 1.00 | STING1 (1.00) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL24354820 | 1.00 | STING1 (1.00) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL23477313 | 1.00 | STING1 (1.00) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL22571165 | 0.95 | STING1 (0.90) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL23798951 | 0.94 | STING1 (0.89) | STING1LMNA | |
| SCHEMBL24453165 | 0.92 | STING1 (0.84) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL24453567 | 0.92 | STING1 (0.84) | STING1LMNAGMNNRAPGEF3BLM | |
| SCHEMBL23476874 | 0.92 | STING1 (1.00) | STING1 | |
| SCHEMBL24453568 | 0.92 | STING1 (0.84) | STING1LMNAGMNNRAPGEF3BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531140-B2 | For therapy or prophylaxis of inflammation or irritation such as is common in the skin disease, atopic dermatitis; cosmetics | E-L MANAGEMENT | 2003-03-11 | — | — | US | claimed |
| US-20020090384-A1 | ANTI-IRRITANT COMPOSITIONS CONTAINING A CYCLIC NUCLEOTIDE | E-L MANAGEMENT | 2002-07-11 | — | — | US | claimed |
| EP-1096938-A1 | ANTI-IRRITANT COMPOSITIONS CONTAINING A CYCLIC 2'-DEOXY-NUCLEOTIDE | E-L Management Corp. (US) | 2001-05-09 | — | — | EP | claimed |
| WO-2000066131-A1 | ANTI-IRRITANT COMPOSITIONS CONTAINING A CYCLIC 2'-DEOXY-NUCLEOTIDE | E-L MANAGEMENT CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| EP-2425023-B1 | REAL-TIME SEQUENCING METHODS AND SYSTEMS | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-12-23 | — | — | EP | disclosed |
| US-9200320-B2 | Real-time sequencing methods and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150105273-A1 | REAL-TIME SEQUENCING METHODS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC (US) | 2015-04-16 | — | — | US | disclosed |
| US-8940507-B2 | Real-time sequencing methods and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-01-27 | — | — | US | disclosed |
| US-20140017680-A1 | Real-Time Sequencing Methods and Systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8501405-B2 | Real-time sequencing methods and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-08-06 | — | — | US | disclosed |
| EP-2425023-A2 | REAL-TIME SEQUENCING METHODS AND SYSTEMS | Pacific Biosciences of California, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20100311061-A1 | REAL-TIME SEQUENCING METHODS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2010129019-A2 | REAL-TIME SEQUENCING METHODS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2008077234-A1 | SYNERGISTIC EFFECTS OF C3, CYCLIC AMP AND CILIARY NEUROTROPHIC FACTOR ON NEURONAL SURVIVAL AND AXONAL REGENERATION | BIOAXONE THERAPEUTIQUE INC. (CA) | 2008-07-03 | — | — | WO | disclosed |