Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205598 | 0.90 | USP2 (0.58) | USP2RAB9ACYP19A1NR3C1KIF11 | |
| SCHEMBL11024025 | 0.87 | KMT2A (0.56) | USP2RAB9ACYP19A1NR3C1MEN1 | |
| SCHEMBL28197455 | 0.87 | MEN1 (0.50) | USP2RAB9ACYP19A1MEN1KMT2A | |
| SCHEMBL11681426 | 0.84 | USP2 (0.66) | USP2RAB9ACYP19A1MEN1KMT2A | |
| SCHEMBL2309836 | 0.83 | USP2 (1.00) | USP2RAB9ACYP19A1MEN1KMT2A | |
| SCHEMBL30927967 | 0.80 | CYP19A1 (0.51) | USP2RAB9ACYP19A1NR3C1 | |
| SCHEMBL29226475 | 0.80 | CYP19A1 (0.51) | USP2RAB9ACYP19A1NR3C1 | |
| SCHEMBL29226478 | 0.80 | CYP19A1 (0.51) | USP2RAB9ACYP19A1NR3C1 | |
| SCHEMBL18084413 | 0.79 | KMT2A (0.45) | USP2RAB9ACYP19A1MEN1KMT2A | |
| SCHEMBL6000168 | 0.79 | USP2 (0.59) | USP2RAB9ACYP19A1LTA4HKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054570-A | NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-3992546-A | 4-Piperidinobutyrophenones as neuroleptics | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |