Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.84 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.84 |
| ▸ | TTR | P02766 | 4/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684948 | 0.92 | SRD5A1 (0.72) | SRD5A2SRD5A1TTRMETAP1HTT | |
| SCHEMBL11684258 | 0.92 | SRD5A2 (0.72) | SRD5A2SRD5A1TTRMETAP1ALDH1A1 | |
| SCHEMBL8253251 | 0.90 | SRD5A2 (0.68) | SRD5A2SRD5A1TTRALDH1A1AKR1B1 | |
| SCHEMBL11686857 | 0.85 | AKR1B1 (0.61) | SRD5A2SRD5A1TTRALDH1A1AKR1B1 | |
| SCHEMBL2601324 | 0.84 | METAP1 (0.60) | SRD5A2SRD5A1METAP1HTTAKR1B1 | |
| SCHEMBL1918142 | 0.82 | SRD5A2 (0.84) | SRD5A2SRD5A1TTRMAPK14PTPRC | |
| SCHEMBL11689203 | 0.81 | SRD5A2 (0.57) | SRD5A2SRD5A1TTRALDH1A1AKR1B1 | |
| SCHEMBL11685606 | 0.81 | MAPK14 (0.60) | SRD5A2SRD5A1TTRALDH1A1MAPK14 | |
| SCHEMBL8256729 | 0.81 | SRD5A2 (0.84) | SRD5A2SRD5A1TTRMETAP1ALDH1A1 | |
| SCHEMBL11683555 | 0.81 | SRD5A2 (0.57) | SRD5A2SRD5A1TTRMETAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041173-A | ANTI-ASTHMATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-09 | — | — | US | disclosed |