Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.54 |
| ▸ | MIF | P14174 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682107 | 0.94 | MAPK14 (0.60) | KDM4EGLASRD5A1SRD5A2MAPT | |
| SCHEMBL17978308 | 0.93 | MAPK14 (0.58) | KDM4EGLASRD5A1SRD5A2MIF | |
| SCHEMBL8253251 | 0.87 | SRD5A2 (0.68) | KDM4ESRD5A1SRD5A2MAPTRAB9A | |
| SCHEMBL5345223 | 0.84 | SRD5A2 (0.61) | KDM4EGLASRD5A1SRD5A2MAPT | |
| SCHEMBL29013394 | 0.83 | MIF (0.72) | KDM4EMIFMAPTSMN1; SMN2RAB9A | |
| SCHEMBL29013391 | 0.83 | MIF (0.72) | KDM4EMIFMAPTSMN1; SMN2RAB9A | |
| SCHEMBL30449720 | 0.83 | MIF (0.72) | KDM4EMIFMAPTSMN1; SMN2RAB9A | |
| SCHEMBL29546448 | 0.83 | MIF (0.72) | KDM4EMIFMAPTSMN1; SMN2RAB9A | |
| SCHEMBL10528326 | 0.83 | KDM4E (0.62) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11686260 | 0.82 | PTPN11 (0.57) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041173-A | ANTI-ASTHMATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-09 | — | — | US | disclosed |