Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143558 | 0.89 | PRSS1 (0.55) | PRSS1F2F10PLAUCA12 | |
| SCHEMBL13901308 | 0.88 | F10 (0.61) | PRSS1NR1H4F2F10PLAU | |
| SCHEMBL8862701 | 0.83 | NR1H4 (0.58) | NR1H4HSD17B10CA12CA1CA2 | |
| SCHEMBL11681875 | 0.82 | F2 (0.55) | PRSS1F2F10PLAU | |
| SCHEMBL2331168 | 0.81 | NR1H4 (0.56) | NR1H4HSD17B10CA12CA1CA2 | |
| SCHEMBL28576874 | 0.81 | PRSS1 (0.52) | PRSS1F2F10PLAUCA12 | |
| SCHEMBL11683322 | 0.80 | PRSS1 (0.55) | PRSS1NR1H4F2F10PLAU | |
| SCHEMBL6648829 | 0.80 | PRSS1 (0.58) | PRSS1F2F10PLAUPRSS2 | |
| SCHEMBL11848927 | 0.79 | NR1H4 (0.57) | NR1H4HSD17B10CA12CA1CA2 | |
| SCHEMBL10143576 | 0.78 | PRSS1 (0.56) | PRSS1F10PLAUPRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016159-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |