Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.56 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683555 | 0.92 | SRD5A2 (0.57) | SRD5A2SRD5A1MAPK14CA12CA1 | |
| SCHEMBL8253251 | 0.86 | SRD5A2 (0.68) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL11684328 | 0.84 | AKR1B1 (0.64) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL11684258 | 0.82 | SRD5A2 (0.72) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL11684846 | 0.82 | MAPK14 (0.67) | SRD5A2SRD5A1MAPK14 | |
| SCHEMBL11683021 | 0.82 | SRD5A2 (0.56) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL11686955 | 0.82 | SRD5A2 (0.72) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL7050731 | 0.82 | TTR (0.58) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL11684035 | 0.82 | SRD5A2 (0.52) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 | |
| SCHEMBL11683249 | 0.82 | SRD5A2 (0.52) | SRD5A2SRD5A1MAPK14ALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041173-A | ANTI-ASTHMATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-09 | — | — | US | disclosed |