Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SPOP | O43791 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11690202 | 1.00 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11682347 | 0.93 | PLCG1 (0.66) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11036803 | 0.92 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11040517 | 0.92 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11036804 | 0.92 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11682103 | 0.92 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11040521 | 0.92 | PLCG1 (0.65) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11650595 | 0.92 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL11650593 | 0.92 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL7765992 | 0.92 | PLCG1 (0.67) | PLCG1L3MBTL1CTDSP1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048160-A | Process for preparation of 7-alkoxy-3-bromomethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |