Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11696110 | 1.00 | MAPK1 (0.55) | MAPK1HTTEGLN1MAPTGAA | |
| SCHEMBL11692408 | 0.99 | MAPK1 (0.54) | MAPK1HTTEGLN1MAPTGAA | |
| SCHEMBL11696558 | 0.89 | MAPK1 (0.46) | MAPK1HTTEGLN1MAPTGAA | |
| SCHEMBL11696567 | 0.89 | MAPK1 (0.46) | MAPK1HTTEGLN1MAPTGAA | |
| SCHEMBL11692381 | 0.87 | MAPK1 (0.51) | MAPK1HTTEGLN1MAPTGAA | |
| SCHEMBL11692388 | 0.87 | MAPK1 (0.51) | MAPK1HTTEGLN1MAPTGAA | |
| SCHEMBL11695040 | 0.84 | MAPK1 (0.40) | MAPK1HTTEGLN1MAPTSMN1; SMN2 | |
| SCHEMBL11695032 | 0.84 | MAPK1 (0.40) | MAPK1HTTEGLN1MAPTSMN1; SMN2 | |
| SCHEMBL11696588 | 0.83 | MAPK1 (0.45) | MAPK1HTTMAPTGAASMN1; SMN2 | |
| SCHEMBL11696598 | 0.83 | MAPK1 (0.45) | MAPK1HTTMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018785-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1977-04-19 | — | — | US | claimed |
| US-4018785-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTIPYRETIC | SHIONOGI & CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |