Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599791 | 0.86 | CYSLTR2 (0.42) | FFAR1GPR84CYSLTR2CYSLTR1TSHR | |
| SCHEMBL28348628 | 0.83 | CYSLTR2 (0.36) | FFAR1GPR84CYSLTR2CYSLTR1PPARG | |
| SCHEMBL18243123 | 0.78 | FFAR1 (0.36) | FFAR1GPR84TSHRCYP3A4CYP2D6 | |
| SCHEMBL3983565 | 0.78 | FFAR1 (0.36) | FFAR1GPR84TSHRCYP3A4CYP2D6 | |
| SCHEMBL21585125 | 0.78 | FFAR1 (0.36) | FFAR1GPR84TSHRCYP3A4CYP2D6 | |
| SCHEMBL11050628 | 0.76 | FFAR1 (0.42) | FFAR1GPR84CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL19712483 | 0.75 | FFAR1 (0.34) | FFAR1GPR84CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL11366354 | 0.74 | ESR1 (0.46) | FFAR1GPR84CYSLTR2CYSLTR1TSHR | |
| SCHEMBL2960467 | 0.74 | FFAR1 (0.35) | FFAR1GPR84CYSLTR2CYSLTR1TSHR | |
| SCHEMBL19013294 | 0.72 | CYSLTR2 (0.47) | FFAR1GPR84CYSLTR2CYSLTR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008261-A | Method of preparing phosphonium siloxanes and products thereof | DOW CORNING CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |